multivelo.tfidf_norm

multivelo.tfidf_norm(adata_atac, scale_factor=10000.0, copy=False)

TF-IDF normalization.

This function normalizes counts in an AnnData object with TF-IDF.

Parameters:

• adata_atac (AnnData) – ATAC anndata object.

• scale_factor (float (default: 1e4)) – Value to be multiplied after normalization.

• copy (bool (default: False)) – Whether to return a copy or modify .X directly.

Returns:

• If copy==True, a new ATAC anndata object which stores normalized counts

• in .X.